Comparison of the Effect of Topical Crystalline Insulin and Oxygen on Bedsore Healing in ICU Patients, A Single Blind Clinical Trial
Authors
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Ismail Tahmasebi Boldaj
Community-Oriented Nursing Midwifery Research Center, Nursing and Midwifery School, Shahrekord University of Medical Sciences, Shahrekord, Iran.
https://orcid.org/0009-0008-6306-5000
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Seyed Lotfollah Afzali-Brojeni
Department of Surgery, Burn and Reconstructive Plastic Surgery Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran.
https://orcid.org/0000-0002-4444-5760
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Farrokh Yadalahi Farsani
Department of Anesthesia, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran.
https://orcid.org/0000-0001-5958-0239
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Ali Hasanpour Dehkordi
Community-Oriented Nursing Midwifery Research Center, Nursing and Midwifery School, Shahrekord University of Medical Sciences, Shahrekord, Iran.
https://orcid.org/0000-0003-4285-8497
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Hadi Raeisi Shahraki
Department of Epidemiology and Biostatistics, Faculty of Health, Shahrekord University of Medical Sciences, Shahrekord, Iran.
https://orcid.org/0000-0003-3071-5587
DOI:
https://doi.org/10.22100/ijhs.v12i3.1289Keywords:
Pressure ulcer, Crystal insulin, Topical oxygenAbstract
Background: Pressure ulcer is an important diagnosis and care need of patients admitted to intensive care units, which in addition to delaying recovery, imposes high costs on the patient and the treatment system. The effectiveness of topical oxygen and insulin has been confirmed in various studies, but so far the two methods have not been compared. The aim of this study was to compare the effect of crystalline insulin and topical oxygen on pressure ulcer healing.
Methods: In this single-blind clinical trial, 60 patients with grade 3 bed sores hospitalized in the intensive care unit of Kashani Hospital in Shahrekord were allocated in 3 groups including the first group (routine treatment and topical regular insulin 100), the second group (routine treatment and local oxygen) and the third group (routine treatments wound washing and camphil dressing) twice daily for two weeks using block randomization method. At previous times, 1 and 2 weeks after the intervention, the condition of the wound was assessed by the Pressure Ulcer Scale for Healing (PUSH) criteria (wound size, wound secretion and tissue type). Data were analyzed by SPSS software.
Results: Before the intervention, the mean wound area, wound secretion, wound degree and PUSH score were not significantly different in the 3 groups. At 1 and 2 weeks after the intervention, the mean wound area, wound secretion, wound grade and PUSH score in the two groups of insulin and local oxygen were not significantly different from each other (P-value>0.05), but compared with the control group was significantly lower (P-value<0.0001).
Conclusion: The use of insulin and topical oxygen caused a significant improvement in bed sores compared to routine treatment and their effects were similar and both are recommended to accelerate bed sores healing in hospitalized patients.
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