International Journal of Health Studies2423-65948220210911 The Role of Professional Behavior to Improve Patient Safety Culture in Clinical Nurses: A Cross-Sectional Study 712 10.22100/ijhs.v8i2.899 EN Seyedmohammad Mirhosseini Nursing and Midwifery Care Research Center, Mashhad University of Medical Sciences, Mashhad, Iran and Department of Psychiatric Nursing, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran. Mohammad Hasan Basirinezhad Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Hossein Ebrahimi Center for Health Related Social and Behavioral Sciences Research, Shahroud University of Medical Sciences, Shahroud, Iran. 20210808 20210911 20210904 Background: Safety culture is one of the most important determinants of patient safety in hospitals. Due to the increasing prevalence of medical errors, increasing public attention, and public opinion pressure on this issue as well as the limitations of studies in this area, the current study was conducted to identify the role of professional behavior to improve patient safety culture in clinical nurses. Methods: This cross-sectional study was performed on 230 nurses in Shahroud Iran. Data collection instruments included a demographic information form, the Hospital Survey on Patient Safety Culture questionnaire, and the Nursing Professional Behaviors Scale. Stratified random sampling was used and data were analyzed by using descriptive and inferential statistics (linear regression analysis). Results: Participants’ mean scores of patient safety culture and professional behavior were 132.51 ±15.97 and 109.57±18.01, respectively. A high score of nurses' professional behavior was directly associated with a higher level of patient safety culture. In addition, the number of working hours per week and change in the workplace were significantly related to patient safety culture level (Pvalue=0.002). Conclusions: Professional behavior is an effective factor in enhancing safety culture in nurses. Therefore, paying attention to the training and proper application of professional behavior in nurses can improve the level of patient safety culture. Keywords: Nurse, Patient safety, Professional behavior