International Journal of Health Studies2423-6594 54 20191220 Evaluation of Relationship between Oral Contraceptive Usages with Psychiatry Symptoms of Premenstrual Syndrome 26 29 10.22100/ijhs.v5i4.692EN Mahsa Majdi Student Research Committee, School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran. Maryam Farjamfar Department of Psychiatric, Imam Hossain Center for Education, Research and Treatment, Shahroud University of Medical Sciences, Shahroud, Iran. Pouneh Zolfaghari Vice-chancellery of Health, Shahroud University of Medical Sciences, Shahroud, Iran. Mehrisadat Mirghasemi B.Sc. of Nursing, Imam Hossain Center for Education, Research and Treatment, Shahroud University of Medical Sciences, Shahroud, Iran. Mohammad Bagher Sohrabi School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran. 20191111 20191220 20191120 Background: Premenstrual syndrome (PMS) refers to a set of physical, psychological or behavioral symptoms occurring in ovulation cycles, which in some ways disturbs a person's activities. The aim of study was to investigate the relationship between previous use of contraceptive pills and psychological symptoms of PMS. Methods: This cross-sectional study was conducted among all female students of Shahroud University of Medical Sciences. Samples were selected by simple census and were provided a standard questionnaire for measuring the PMS. Significant level was set at 0.05. Results: 65.5% of the participants had some degree of PMS. The use of OCP significantly reduced some PMS related symptoms such as depression (Pvalue=0.039), sadness (Pvalue=0.012), sobering up (Pvalue=0.003) and anger (Pvalue=0.032). Conclusions: The results of this study showed the use of OCP can clearly and significantly reduce some of the symptoms associated with PMS, such as depression, sadness and sobering up, and anger. Key words: PMS, OCP, Psychiatry Symptoms.